Research protocols:
New approaches to vascular/valvular Interventional therapies through novel utilization of devices in coronary, peripheral vascular disease and Aortic valve disease.Novel approaches to critical limb ischemia, Diabetic foot and chronic Stasis syndromes for limb salvage. Diabetic limb salvage program through triple prong approach for Vasculopathy, Venous capillary insufficiency and peripheral neuropathy.
Discovered Dysautonomia Syndromes- PPS (Paradoxic Parasympathetic Syndrome), Hypervagotonia, Autonomic orthostasis and their clinical application in evaluation and treatment of various conditions such as Diabetes-ll, Diabetic vasculopathy and nephropathy and cardiovascular complications, Systemic Inflammatory vasculopathy, Coagulopathy, RSD / EM, Rest Less Leg Syndrome, Metabolic Syndrome, CFS, PTSD, ADD/ADHD, Dilated cardiomyopathy and congestive heart failure, Cardiac arrhythmias – Atrial fibrillation, Supra Ventricular Tachycardia and secondary prolonged QT syndrome.
Discovered Central clinical autonomic loop as the central regulating mechanism for autonomic system.
Developed novel non-invasive algorithm and testing for assessing coronary artery disease and severity of coronary artery disease.
PATENTS: Designed and patented four endovascular devices awaiting to be developed for clinical use.
1) Clover cutting balloon for aortic valvuloplasty
2) Motorized Nitinol guide wire for atherectomy
3) Focused Cutting balloon for controlled PTCA
4) Athero-Thrombectomy device
5) Patented breathing exercise program - Alternating Autonomic Breathing (AAB) exercise to reset autonomic imbalance, as an adjuvant to pharmacologic interventions, in treating dysautonomia.